Bone Formation Biomarker Detection Service
Creative BioMart Biomarker is one of the experts who are professional in biomarker detection. We have years of biomarker detection experience and advanced detection methods and detection instruments to provide fast, sensitive and repeatable bone formation biomarker detection services according to customer needs. Our services also include bone resorption biomarker detection services and cartilage diseases and arthritis biomarker detection services.
Introduction
Our bones are constantly undergoing bone remodeling in response to mechanical loads, micro-damage repair and mineral homeostasis. Bone remodeling is a cyclical process necessary for bone growth and consists of four phases: resorption, reversal, formation, and a resting phase. In a typical cycle, the resorption phase lasts about 7-10 days, while the formation phase takes 2-3 months. The bone cells that function in this process are mainly osteoclasts, osteoblasts and osteocytes. Bone markers are divided into bone formation markers and bone resorption markers. Bone formation biomarkers are produced by metabolism of osteoblasts or derived from procollagen metabolism. The bone biomarker is released from the bone into the blood or urine, reflecting the activity of the bone formation. The detection of Bone formation markers is mainly used to monitor the bone remodeling process and predict bone-related diseases. Bone formation markers include BAP, Calcium, CICP, PTH, OC, OPG, OPN, PINP, 1,25-dihydroxy vitamin D, 25-hydroxy vitamin D and vitamin K. Biomarker detection methods mainly include ELISA, RIA, HLPC, ECL, etc.
Figure 1. Bone circulation
Creative BioMart Biomarker offers a wide range of bone formation related biomarker detection based on customer needs. Through advanced instruments, we accept different samples of different concentrations and ensure a wide kinetic range to detect samples of different concentrations. In addition, different biomarkers have different detection effects in different samples, we can customize the detection plan according to customer needs, and obtain the ideal test results with appropriate samples and advanced detection methods.
Our Advantages
- Accept a wide range of sample types
- Provide multiple detection methods
- Ensure high sensitivity for detecting in different samples
- Ensure high accuracy and repeatable detection
- Ensure a wide kinetic range to detect samples of different concentrations
- Short experimental period
Our Single Biomarker Detection Services Related to Bone Formation:
Workflow of Biomarker Detection at Creative BioMart Biomarker
Creative BioMart Biomarker strictly controls each specific experimental step in the detection procedure to ensure high sensitivity, high accuracy and repeatable bone formation biomarker detection.
Please feel free to contact us if you would like to know more about bone formation biomarker detection. At Creative BioMart Biomarker, we not only provide high-quality bone formation biomarker detection service, but also provide detection services for other biomarkers. Additionally, our experts can also provide and help design a proper technological scheme according to your specific requirements.
Reference:
- Hlaing, T.T.; Compston, J.E. Biochemical markers of bone turnover – uses and limitations. Ann Clin Biochem. 2014, 51(Pt 2): 189-202.
