Cellular Biomarker Analysis

Cellular biomarkers allow cells to be isolated, sorted, quantified, and characterized by their morphology and physiology. They have been used in both clinical and laboratory settings, and can be discriminated between a large sample of cells based on their antigens. With years’ experience in cell culture and analysis, our company provides many different services to assist researchers with cell biomarker discovery and analysis.

Flow Cytometry and Cell-Based Assays

Flow cytometry is a highly versatile method not only in the discovery of new biomarkers but also in clinical validation and routine implementation. At our company, we use flow cytometry to perform immunophenotyping, cell counting, and numerous cell function assessments, such as intracellular cytokine production, protein phosphorylation, cell proliferation, and apoptosis.

Besides flow cytometry, our company also offers a full range of cell-based assays including cell proliferation assays, cell death assays, reporter gene assays, and cell signaling assays. Our cell-based assays can be used to test cytotoxicity, or to determine drug potency and the mechanism of action. They can be fully customized in line with all relevant regulatory guidelines and recommendations.

Rare Cell Analysis

Rare cells are low-abundance cells in a much larger population of background cells. They are highly important for various applications including diagnosis and prognosis of many cancers, prenatal diagnosis, and diagnosis of viral infections. Our company offers a compressive and flexible platform for rare cell analysis that is highly sensitive and specific. It can accommodate either fixed or live cell samples, which enables deep phenotyping and highly customized biomarker analysis.

Primary Cell Isolation and Culture

Our company also offers primary cell isolation and culture services to support researchers in biomarker discovery and analysis. Compared to cell lines, primary cell culture is able to generate more biologically relevant data. They can be isolated from oncology and other disease populations, and can be applied in assay development and the identification of diagnostic and prognostic biomarkers.

Our cellular biomarker discovery and analysis services not only include versatile analytical techniques, but also incorporate all necessary supporting techniques such as primary cell isolation and culture. Our team possesses expertise with both primary cell and transformed cell lines. If you are interested in our services, please do not hesitate to contact us for further information.

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