Molecular Biomarker Analysis

Molecular biomarkers have been identified as biomarkers that can be discovered using basic and acceptable platforms such as genomics and proteomics. Many of these techniques are available for biomarker discovery. Apart from genomics and proteomics platforms of biomarker assay techniques, metabolomics, lipidomics, glycomics, and secretomics are the most commonly used as techniques in identification of biomarkers. Our company provides a variety of services to discover and analyze molecular biomarkers such as genes, proteins, and hormones.

Molecular Assays

Molecular assays are a collection of techniques that are used to analyze molecular biomarkers in genome and proteome. These techniques are used to diagnose and monitor disease, detect risk, and decide which therapies will work best for individual patients.

Our molecular assays include in vitro assays such as PCR-ELISA or Fluorescence in situ hybridization (FISH). The assay detects a molecule, often in low concentrations, that is a biomarker of disease or rick in a sample taken from a patient. Our company also applies real-time PCR, direct sequencing, microarray chips and MALDI-TOF techniques to detect molecular biomarkers. We also provide high-throughput protein arrays that use complementary DNA or antibodies to bind and detect many different proteins in parallel.

Gene Mutation Analysis

Gene mutation analysis plays an essential role in various areas of genetic diagnosis. Our company provides many up-to-date techniques to identify genetic mutations, which include direct sequencing, DNA hybridization, and restriction enzyme digestion methods. We also offer high-speed and high-throughput next-generation sequencing (NGS) service for both qualitative and quantitative DNA sequence data.

Chromatography and Mass Spectrometry

Chromatography and mass spectrometry are extremely powerful techniques for molecular biomarker studies. Our company provides services for both biomarker separation and detection. Our molecule separation techniques include gas chromatography (GC), high performance liquid chromatography (HPLC), and capillary electrophoresis (CE). And our molecular detection techniques include ESI-MS, DESI-MS, 2D-DIGE-MS, SELDI-TOF (MALDI-TOF), and immunoprecipitation MS.

Nuclear Magnetic Resonance

NMR metabolomics has made significant contributions to the identification of biomarkers to aid in the diagnosis and treatment of various human diseases. Our NMR techniques have many appealing advantages for biomarker discovery, which include the simple sample preparation, and the robust, versatile, and easy applications. Our company provides one-dimensional NMR and two-dimensional NMR services with excellent analytical reproducibility.

Creative Biomart Biomarker supports researchers to efficiently identify and validate molecular biomarkers. Our biomarker discovery and analysis services are highly customizable according to the specific requirements from the customers. Please do not hesitate to contact us for more details about our molecular biomarker services.

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