Proteomics Service for Biomarker Analysis
Proteomics, the large-scale study of proteins, has become a powerful tool in the field of biomarker analysis. Proteomics enables the detection, identification, quantification and characterization of proteins, providing valuable insights into disease mechanisms, diagnosis and treatment. Creative BioMart Biomarker provides proteomics services with unique advantages in biomarker research.
Proteomics and Biomarkers
Proteomics refers to the comprehensive analysis of proteins in biological samples. It involves the study of protein expression levels, post-translational modifications, interactions and functions. Proteomics enables a deeper understanding of cellular processes, disease mechanisms, and the identification of potential biomarkers for a variety of diseases, including cancer, cardiovascular, and neurological disorders.
Proteomics complements genomics by focusing on the dynamic properties of proteins and their functional role in biological systems. It enables researchers to unravel complex networks of protein interactions and reveal molecular pathways involved in disease progression and treatment response.
Proteomics offers numerous opportunities for biomarker discovery and validation. By comparing protein profiles between healthy and diseased samples, researchers can identify proteins that are differentially expressed, post-translationally modified, or associated with a particular disease state. These identified proteins can serve as potential biomarkers reflecting disease onset, progression, or treatment response.
Proteomics Services Offered by Creative BioMart Biomarker
At Creative BioMart Biomarker, we are at the forefront of proteomics research and provide comprehensive services for biomarker analysis.
2-DE is a widely used technique for protein separation based on their isoelectric point (pI) and molecular weight. It involves separating proteins by charge in a first dimension using isoelectric focusing (IEF), followed by size in a second dimension using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE).
Liquid chromatography is a versatile technique for the separation of proteins in proteomics. It exploits differences in chemical properties, such as hydrophobicity, polarity, or affinity, to separate and fractionate complex protein mixtures. Used in conjunction with MS, LC enables the identification and quantification of proteins with high sensitivity and resolution.
Mass spectrometry plays a central role in proteomic analysis by enabling the identification, quantification, and characterization of proteins. It involves ionizing proteins or peptides, separating the ions based on their mass-to-charge ratios, and detecting their abundance. We provide MS technology services such as matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) MS, electrospray ionization (ESI)-MS, and tandem MS (MS/MS).
The Flow of Proteomics Service
Our Advantages
- Extensive proteomics knowledge and expertise.
- Advanced proteomics analysis instruments and technologies enable us to provide accurate and reliable results.
- Provide end-to-end proteomics services, from sample preparation and protein isolation to mass spectrometry-based analysis and data interpretation, ensuring a seamless and efficient workflow.
- Use advanced algorithms and bioinformatics tools to extract meaningful information from complex data sets and identify potential biomarkers with high precision.
Creative BioMart Biomarker's expertise, advanced technologies, comprehensive services and bioinformatics capabilities place us at the forefront of proteomics research. Feel free to contact us to find out how you can pave the way for your biomarker research with our proteomics services.
