All-Liquid Separations Service

Among the variety of separation techniques available, all-liquid separations have emerged as powerful tools for the isolation and analysis of biomarkers from complex biological samples. Creative BioMart Biomarker provides professional services in the field of biomarkers, including all-liquid separation services.

What is All-Liquid Separations?

All-liquid separations, also known as liquid-liquid extractions or solvent-based separations, are a group of advanced separation techniques used to purify and separate components from complex liquid mixtures. The method relies on the differential solubility of analytes in two immiscible liquid phases. The sample is partitioned between these two phases based on their respective solubility, allowing selective enrichment and isolation of biomarkers of interest. This powerful method offers high sensitivity, selectivity, and precision, making it indispensable in biomarker research.

All-Liquid Separations Service Offered by Creative BioMart Biomarker

Creative BioMart Biomarker provides all-liquid separation services tailored to the specific needs of biomarker research. Our all-liquid separation services cover a variety of technologies, each with its own unique advantages in biomarker analysis.

• Liquid-Liquid Extraction: The basic technique of all-liquid separation, liquid-liquid extraction involves the transfer of analytes from one liquid phase (such as the sample matrix) to another immiscible liquid phase (usually an organic solvent). We utilize advanced equipment and optimized protocols to achieve efficient and repeatable liquid-liquid extraction.
• Countercurrent Chromatography (CCC): We use CCC, a powerful liquid-liquid chromatography technique, to perform high-resolution separations without the need for a solid stationary phase. This technique is particularly useful for biomarker studies where sensitivity and precision are critical.
• Solid-Phase Microextraction (SPME): Our SPME technique involves the extraction of analytes from a liquid phase onto a solid sorbent coated on fibers. This solvent-free approach is ideal for biomarker studies where the amount of sample available is limited.
• Cloud-Point Extraction (CPE): We offer an environmentally friendly and cost-effective CPE service that utilizes the formation of micelles to isolate analytes for efficient preconcentration and purification.

Application of All-Liquid Separations in Biomarker Research

• Detect low-abundance analytes, even in complex biological matrices such as blood, urine, and tissue.
• Effectively remove unwanted matrix interferences, ensuring cleaner samples and reducing the risk of false or missed negatives.
• Preconcentrate analytes for more efficient and sensitive downstream analysis, such as mass spectrometry or nuclear magnetic resonance (NMR).
• Easily automated, making it suitable for high-throughput biomarker research, reducing analysis time and increasing efficiency.

Why Choose Creative BioMart Biomarker for All-Liquid Separations Service?

• Our expert team takes care of sample collection, storage and pretreatment to remove potential contaminants and ensure accurate and reproducible results.
• High-throughput processing is possible with cutting-edge solutions for all-liquid separations.
• Design custom all-liquid separation methods to meet specific research goals, ensuring optimal results and meaningful data.
• Maintain strict confidentiality agreements and strong data security measures to ensure all information is protected.

Workflow of All-Liquid Separations Service

Creative BioMart Biomarker focuses on providing one-stop solutions for biomarkers. After all-liquid separation, we provide comprehensive analysis using advanced technologies such as mass spectrometry, high performance liquid chromatography (HPLC) and gas chromatography (GC). If you are interested in our services, please feel free to contact us.