Biomarkers are measurable indicators of the severity or presence of some disease state. They can be used to screen for, diagnose, or monitor the activity of disease and to guide molecularly targeted therapy or assess therapeutic response. Biomarkers can be specific cells and tissues, or molecules such as genes, enzymes, or hormones. Complex organ functions or general characteristic changes in biological structures can also act as biomarkers. Even though the term biomarker is relatively new, biomarkers have been used in pre-clinical research and clinical diagnosis for a considerable time. For example, cholesterol values are widely known as a biomarker and risk indicator for coronary and vascular disease.
Biomarkers can take many forms, and as a consequence a variety of strategies have been adopted for their discovery and analysis. Our company offers a variety of services to discover and analyze biomarkers in preclinical and clinical samples including biological fluids such as plasma, serum, urine, tissue, and CSF. We provide support for projects at every stage in the development pipeline, from initial biomarker identification, qualification, and validation through to downstream clinical applications. Our biomarker services include:
Molecular Biomarker Analysis
- Molecular assays
- Gene mutation analysis
- Chromatography and mass spectrometry
- Nuclear magnetic resonance
Cellular Biomarker Analysis
- Flow cytometry and cell-based assays
- Rare cell analysis
- Primary cell isolation and culture
Tissue Biomarker Analysis
- Custom tissue microarray
- Histology, digital pathology and image analysis
Creative Biomart Biomarker is your ideal partner, who can provide you a broad spectrum of services to discover and analyze different-form biomarkers. Our laboratory is equipped with the latest technologies to perform customized biomarker studies. Our highly experienced experts apply systematic and scientifically-rigorous approaches to biomarker discovery and analysis, which gives solutions to complex translational questions. If you are interested in our services, please feel free to contact us for further information.
