Transcriptome Profiling Service
In an era of unprecedented advances in biomedical research, the combination of genomics and precision medicine provides us with a range of tools to unravel the mysteries of human health and disease. Transcriptome profiling is one such breakthrough technology that has become a beacon of hope in the quest to identify genetic biomarkers that underpin different medical conditions. Creative BioMart Biomarker provides customers with comprehensive transcriptome profiling services to advance genetic biomarker research.
What is Transcriptome Profiling?
Transcriptome profiling provides a complex panoramic view of the dynamic interactions of genes within cells. This sophisticated approach provides a comprehensive profile of all RNA molecules expressed in a given tissue or cell population. By deciphering the transcriptome (the complete set of RNA produced by an organism), we can gain insight into which genes are actively transcribed and translated into functional proteins.
An important method of transcriptome profiling is next-generation sequencing (NGS) technology, a revolutionary method that has changed our ability to decipher genetic information. NGS enables researchers to explore the transcriptome without any preconceived notions, thereby discovering new genes and previously unknown RNA isoforms. Through meticulous sequencing and quantitative analysis, detailed RNA expression profiles were constructed.
Transcriptome Profiling Service Offered by Creative BioMart Biomarker
At Creative BioMart Biomarker, our genetic biomarker transcriptome profiling service demonstrates our commitment to advancing precision medicine. With our array of technologies at our disposal, we work to uncover the genetic clues behind disease and pave the way for tailored therapeutic interventions.
Our services cover the entire workflow from experimental design to data analysis. Through innovative computational analyses, we screen data to pinpoint genetic signatures that distinguish healthy and diseased states.
- Microarray Analysis: DNA probes representing specific genes are immobilized on a solid surface. Complementary RNA molecules in the sample bind to these probes to the extent that they can provide insight into the expression levels of the corresponding genes.
- NGS Technology: RNA sequencing (RNA-seq) quantifies the entire transcriptome, enabling the discovery of novel biomarkers and a deeper understanding of gene regulation. RNA-seq can identify alternative splicing events, single nucleotide polymorphisms (SNPs), and fusion genes, all of which can contribute to disease development.
- Differential Gene Expression Analysis: compare expression levels between different samples. This can identify genes that are up- or down-regulated under specific conditions, providing clues to potential biomarkers.
- Single-cell Transcriptomics: Capable of capturing subtle differences in gene expression in individual cells. This is especially critical for understanding cellular heterogeneity within tissues, unraveling rare cell populations, and deciphering complex developmental pathways.
Application of Transcriptome Profiling in Genetic Biomarker Research
- Deciphering genetic signatures that classify cancer subtypes and predict response to treatment.
- Unraveling the mysterious mechanisms that lead to diseases like Alzheimer's and Parkinson's.
- Identify genetic biomarkers predictive of cardiovascular disease to guide tailored interventions.
- Identify early immune responses and discover biomarkers that indicate the severity of infectious disease.
Why Choose Creative BioMart Biomarker?
- Expertise: Our team is made up of outstanding researchers, bioinformaticians and geneticists.
- Cutting-edge Technology: We have a series of advanced technologies that enable us to decipher the transcriptome with high precision.
- Comprehensive Services: From experimental design to data analysis, we provide end-to-end solutions.
Workflow of Transcriptome Profiling Service
If you are interested in our services, please feel free to contact us.
