Pulmonary Biomarker Detection Service

Creative BioMart Biomarker is one of the well-recognized experts who is professional in biomarker detection. We have years of biomarker detection experience and advanced detection methods and detection instruments to provide fast, sensitive and repeatable pulmonary biomarker detection services according to customer needs. Our services also include kidney injury biomarker detection services, liver injury biomarker detection services and cardiovascular biomarker detection services.

Introduction

Interstitial lung diseases (ILDs) are a class of disorders of the lungs whose main characteristics include cell proliferation, interstitial inflammation, fibrosis, or a combination of these within the alveolar wall. If the cause is not identified, the patient will be diagnosed as idiopathic interstitial pneumonia (IIP). IPF, respiratory bronchiolitis interstitial lung disease/desquamative interstitial pneumonia (RB-ILD/DIP), idiopathic non-specific interstitial pneumonia (iNSIP) and cryptogenic organizing pneumonia (COP) are members of idiopathic interstitial pneumonias (IIPs). The most common type of IIP is idiopathic pulmonary fibrosis (IPF), a chronic progressive fibrosing interstitial pneumonia of unknown cause, occurs mainly in older adults IPF biomarkers are important for predicting disease progression and treatment response, and for differential diagnosis. IPF biomarkers are mainly divided into three categories, including biomarkers related to alveolar epithelial cell dysfunction (such as KL-6 antigens, carbohydrate antigen (CA) 15-3, CA125, mucin MUC5B and surfactant proteins A and D), biomarkers related to extracellular matrix remodeling and fibroproliferation (such as matrix metalloproteinase-1 (MMP-1) and -7 (MMP-7), lysyl oxidase-like2 and periostein ), and biomarkers related to immune dysfunction (such as CC chemokine ligand-18 and YKL-40).

Core mechanisms and candidate molecular biomarkers for idiopathic pulmonary fibrosis.Figure 1. Core mechanisms and candidate molecular biomarkers for idiopathic pulmonary fibrosis.

Creative BioMart Biomarker offers a wide range of pulmonary related biomarker detection based on customer needs. Through advanced instruments, we accept different samples of different concentrations and ensure a wide kinetic range to detect samples of different concentrations. In addition, different biomarkers have different detection effects in different samples, we can customize the detection plan according to customer needs, and obtain the ideal test results with appropriate samples and advanced detection methods.

Our Advantages

  • Accept a wide range of sample types
  • Provide multiple detection methods
  • Ensure high sensitivity for detecting in different samples
  • Ensure high accuracy and repeatable detection
  • Ensure a wide kinetic range to detect samples of different concentrations
  • Short experimental period

Our Single Biomarker Detection Services Related to Pulmonary Disease (including but not limited to the following):

  • Fibrinogen Detection Service
  • KL-6 Detection Service
  • MMP-1 Detection Service
  • MMP-7 Detection Service
  • Surfactant Protein A Detection Service
  • Surfactant Protein D Detection Service
  • Tenascin C Detection Service
  • CCL-18 Detection Service

Workflow of Biomarker Detection at Creative BioMart Biomarker

Creative BioMart Biomarker strictly controls each specific experimental step in the detection procedure to ensure high sensitivity, high accuracy and repeatable pulmonary biomarker detection.

Pulmonary Biomarker Detection Service

Please feel free to contact us if you would like to know more about pulmonary biomarker detection. At Creative BioMart Biomarker, we not only provide high-quality pulmonary biomarker detection service, but also provide detection services for other biomarkers. Additionally, our experts can also provide and help design the best solution according to your specific requirements.

References:

  1. Ballester, B.; et al. Mucins as a New Frontier in Pulmonary Fibrosis. J Clin Med. 2019, 8: 1447.
  2. Ley, B.; et al. Molecular biomarkers in idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2014, 307: L681–L691.

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