Creative BioMart Biomarker is one of the experts who are professional in biomarker detection. We have years of biomarker detection experience and advanced detection methods and detection instruments to provide fast, sensitive and repeatable kidney injury biomarker detection services according to customer needs. Our services also include liver injury biomarker detection services, pulmonary biomarker detection services, cardiovascular biomarker detection services, etc.
The kidneys are a pair of bean-shaped organs that are located in the abdominal cavity on both sides of the human waist. The smallest functional unit of the kidney is the nephron, which consists of the renal corpuscle and the renal tubule. The renal corpuscle is composed of the glomerulus and the Bowman’s capsule, and the renal tubule is composed of the proximal convoluted tubule, the loop of Henle, the distal convoluted tubule, and the connecting tubule. The kidney is an important organ belonging to the human urinary system and has a variety of physiological functions, including the excretion of metabolic wastes, poisons and drugs, the regulation of water balance, the osmotic pressure balance, acid-base balance, and electrolyte concentration. Kidney damage can be caused by a variety of factors, such as allograft rejection and metabolic disease (e.g. diabetes mellitus). Kidney damage can affect kidney function and lead to a variety of diseases, for instance, acute kidney injury (AKI), chronic kidney disease (CKD), and diabetic nephropathy (DN). The proper use of kidney injury related biomarkers can help to predict kidney injury early and estimate the severity degree of kidney damage. At the same time, monitoring these biomarkers can help optimize the treatments and improve the management of patients with kidney disease. Creative BioMart Biomarker offer detection services for multiple biomarkers, of which cystatin C and albuminuria are biomarkers related to glomerular injury, while kidney injury molecule-1 (KIM-1), liver-type fatty acid binding protein (L-FABP), neutrophil gelatinase-associated lipocalin (NGAL), α1- microglobulin (A1M), and β2- microglobulin (B2M) are biomarkers related to renal tubular injury. In short, biomarkers related to kidney injury have development potential in the diagnosis and treatment of kidney diseases.
Figure 1. Physiology of biomarkers of AKI (Schaub, et al. 2016)
Creative BioMart Biomarker offers a wide range of kidney injury related biomarker detection based on customer needs. Through advanced instruments, we accept different samples of different concentrations and ensure a wide kinetic range to detect samples of different concentrations. In addition, different biomarkers have different detection effects in different samples, we can customize the detection plan according to customer needs, and obtain the ideal test results with appropriate samples and advanced detection methods.
Creative BioMart Biomarker strictly controls each specific experimental step in the detection procedure to ensure accurately quantify the level of biomarkers related to kidney injury in each sample.
At Creative BioMart Biomarker, we not only provide high-quality kidney injury biomarker detection service, but also provide detection services for other biomarkers. Additionally, our experts can also provide and help design a proper technological scheme according to your specific requirements. Please feel free to contact us, Creative BioMart Biomarker is here to offer you professional and thoughtful service.