Pharmacodynamic Biomarker Assays Service

Pharmacodynamic (PD) biomarkers are an important part of targeted therapy and drug development, and can provide important information for related research. Therefore, the research of PD biomarkers is necessary for many researchers. As an expert in the field of biomarker services, Creative BioMart Biomarker has an experienced team of experts and technical teams, as well as a variety of advanced technical platforms that can be used for PD biomarker researches.

PD biomarker refers to a biomarker that can provide useful information for the pharmacological effect of the drug on the target in the body. It can be used in drug treatment programs or targeted therapy in disease research, and to monitor the biological effects of drug development. PD biomarker research is often combined with drug development to select a reasonable combination of targeted drugs and optimize the combination drug program. Targeted therapy is the current research focus of disease treatment, and has become a new research direction for various disease treatment methods. At the same time, targeted drugs are also an important development direction for new drug development, especially in tumor-related clinical research. PD biomarkers can not only provide information on whether the drug has reached the expected target to help prove the mechanism of the drug, but also can provide information on whether the drug target can change the biology of the tumor. In addition, the research of PD biomarkers is helpful for the selection of the best biological dose and understanding the drug resistance mechanism. PD research can be used to evaluate the function and molecular effects of targeted drugs in tissues, and it can be performed directly on tumor specimens. With the development of targeted therapy and targeted drugs, PD biomarkers have increasingly important roles and research prospects. The research of PD biomarkers helps to incorporate PD endpoints in clinical trials, and can provide new insights into drug effect studies, dose studies, mechanism studies, and biological response studies. However, PD biomarkers need to be further studied, and we provide corresponding services to help customers in-depth exploration of PD biomarkers.

Five essential characteristics of PD biomarker for biosimilarsFigure 1. Five essential characteristics of PD biomarker for biosimilars (Li, et al. 2019)

Our Services for PD Biomarker Assay (including but not limited to the following):

  • Confirming Mechanism of Action
  • Efficacy Predicting Service
  • Immunotoxicity Assay Service

Our Advantages

  • Multiple technical platforms for PD biomarker assays
  • Experienced technical team
  • Strict and standard experimental operation
  • Professional PD analysis
  • High quality and more efficient custom services
  • Short service cycle and more competitive prices

Workflow of Custom Biomarker Service at Creative BioMart Biomarker

Pharmacodynamic Biomarker Assays Service

At Creative BioMart Biomarker, we provide customers with high-quality custom biomarker service related to PD biomarker assays, and our expert team can customize scientific and rigorous experimental programs as soon as possible according to customer research needs and sample types. Our technical team has many years of experience in PD biomarker assays and has been strictly controlling each process to ensure that customers are provided with accurate, precise, and repeatable detection results. If you are seeking related services, Creative BioMart Biomarker may be your ideal choice, please feel free to contact us for more information.

References:

  1. Gainor, J. F.; et al. Pharmacodynamic biomarkers: falling short of the mark? Clinical Cancer Research. 2014, 20(10): 2587-2594.
  2. Li, J.; et al. Advancing biosimilar development using pharmacodynamic biomarkers in clinical pharmacology studies. Clinical Pharmacology & Therapeutics. 2019, 107(1): 40-42.

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