Gene Expression and Localization Service

Gene expression refers to the genetic information stored in the DNA sequence which is transcribed and translated into biologically active protein molecules by cells during life. Only the normal expression of genes can make DNA play a genetic role and show specific apparent traits. The process of transforming and modifying the genetic material-DNA of an organism at the molecular level is a means of studying gene function, gene expression regulation mechanism, producing recombinant proteins and antibodies, designing disease models and screening new drugs. Gene localization refers to the determination of the linked group or chromosome to which a gene belongs and the position of the gene on the chromosome. Gene location is an important link in genetics research and a basic work in genetics research.

Gene expression profiling and protein subcellular localization are often used to analyze protein interactions. Studies have shown that the gene expression profiles of interacting proteins are highly similar and have the same subcellular localization.

Gene Localization Services

  • Somatic cell hybridization method (cell fusion)
  • When cells are fused, only a small amount of cells in the culture fluid are fused into hybrid cells. It is necessary to select and purify hybrid cells, that is, to create a culture environment that is only suitable for the survival of hybrid cells and causes the death of parent cells. Creative BioMart Biomarker provides a variety of selection systems for you to choose from, including HAT selection system and cloning panel method (i.e. hybrid cloning).

  • In situ hybridization service
  • The in situ hybridization and fluorescence in situ hybridization services performed according to the principle of base complementary pairing can locate the genetic location such as the insulin gene.

  • Chain analysis
  • According to the linear arrangement of genes on the chromosome, the characteristics of the linked gene and another gene or genetic marker on the same chromosome are used for positioning.

Gene Expression Profiling Services

Gene expression refers to the transformation of genetic material stored in DNA into biologically active gene products during the life of a cell. Cells control their structure and function by regulating the expression of genes. Creative BioMart Biomarker provides a variety of gene expression testing services, the main services are not limited to the following categories:

  • mRNA level: qPCR, in situ hybridization, gene expression profiling, miRNA chip service, etc.
  • Protein level: Western Blot, Northern Blot, IHC, IF, ELISA, flow cytometry service, protein chip, etc.
  • Gene mutation verification: Multiplex PCR, sequencing, restriction digestion, etc.

Service Process

  1. The customer provides the gene-related materials to be tested and agrees on the experimental plan
  2. Sign a technical service contract and agree on service charges and mission deadlines
  3. Conduct test services
  4. The company sorts the results back to the customer
  5. Feedback on customer-related service quality

Creative BioMart Biomarker is a professional organization engaged in life science research, product development, new drug preparation, pathology research and experimental technical services. It has been engaged in gene expression services and gene diagnosis for many years and is one of the gene expression and localization service technology service providers. The entire service process is transparent and the results are safe and stable. Creative BioMart Biomarker welcomes customers to consult, and sincerely invites laboratories to cooperate and develop together.

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