Desorption Electrospray Ionization-Mass Spectrometry Service
Biomarkers are molecular entities that can be employed to diagnose, prognosticate, and track the trajectory of maladies. The identification of biomarkers is of paramount importance for the formulation of efficacious therapeutics and the provision of personalized healthcare. A cutting-edge analytical technique that has been gaining traction in biomarker studies is desorption electrospray ionization-mass spectrometry (DESI-MS), which boasts the unique capacity to quantify biomolecules in intricate biological matrices with exceptional sensitivity and specificity. Creative BioMart Biomarker offers a top-notch DESI-MS service that can be leveraged to fortify biomarker studies, ensuring the high caliber of investigative prowess.
Desorption Electrospray Ionization-Mass Spectrometry and Biomarker
DESI-MS is a cutting-edge ambient ionization technique that is highly versatile and can analyze a wide range of samples, including tissues, cells, and body fluids. DESI-MS combines the principles of electrospray ionization (ESI) and desorption (DI) by using a charged solvent spray to desorb and ionize analytes from a sample surface. The ions are then transferred to the mass spectrometer for analysis.
DESI-MS is increasingly used in biomarker studies due to its ability to analyze complex biological samples with high sensitivity and specificity. The technique has been used to identify biomarkers in various diseases, including cancer, diabetes, and cardiovascular disease. Biomarker discovery and validation are pivotal steps in developing diagnostic and prognostic tests for various diseases. In biomarker research, DESI-MS can be used to detect biomolecules such as lipids, proteins, and metabolites, making it ideal for analyzing complex biological samples.
Figure 1. Operating principles of DESI-MS. (Halouzka, R.; et al. 2020)
Desorption Electrospray Ionization-Mass Spectrometry Services
Our DESI-MS services for biomarker analysis comprise a range of techniques, including biomarker discovery, biomarker validation, and quantitative analysis.
- Biomarker discovery: With our DESI-MS services, we can analyze your tissue samples to identify potential biomarkers for your disease of interest, using a high degree of perplexity to decipher the underlying molecular mechanisms.
- Biomarker validation: We can further validate potential biomarkers identified in discovery studies using larger sample sets to ensure their specificity and sensitivity, using a high degree of burstiness to quickly confirm the initial findings.
- Quantitative analysis: We can quantify the levels of biomolecules within tissues, enabling the identification of biomarkers for disease progression and treatment response with a high degree of efficiency.
Our Advantages
- Enables rapid and highly sensitive detection for easy analysis of a large number of biomolecules, including lipids, peptides, and metabolites.
- Our team of skilled and experienced scientists and analysts are proficient in DESI-MS analysis and have a vast knowledge of biomarker research.
- Using cutting-edge instruments and techniques to ensure the accuracy and reproducibility of results.
- Tailor-made services are provided according to the specific needs of customers, including sample preparation, data analysis and interpretation.
Creative BioMart Biomarker provides a range of DESI-MS services for biomarker research, catering to the needs of clients and delivering accurate results. Our cutting-edge technology and skilled team of experts can help accelerate biomarker discovery and development. Don't hesitate to reach out to us for more details.
Reference:
- Halouzka, R.; et al. Analytical methods in strigolactone research. Plant Methods. 2020, 16: 76.
