Nuclear Magnetic Resonance Service

Creative BioMart Biomarker offers a multifarious assortment of analytical techniques to aid in the discernment and confirmation of biomarkers. Among the panoply of approaches, one technique stands out for its formidable analytical prowess: Nuclear Magnetic Resonance (NMR). This robust and versatile tool has emerged as a preeminent instrument in biomarker investigations, owing to its ability to facilitate the elucidation of intricate biochemical structures and discern subtle molecular interactions. Creative BioMart Biomarker is committed to providing the high quality NMR service available, serving as an invaluable ally to researchers who seek to advance the frontiers of biomarker research.

Nuclear Magnetic Resonance and Biomarker

NMR, a spectroscopic technique of formidable analytical prowess, leverages the magnetic atomic nuclei to investigate the physical and chemical properties of materials. Under the action of an external magnetic field, the spin nucleus absorbs the energy of the electromagnetic wave and transitions from a lower energy level to a higher energy level, and energy exchange occurs. The obtained absorption spectrum is a nuclear magnetic resonance spectrum.

In biomarker studies, NMR serves as a potent and versatile tool for identifying and quantifying small molecules in biological samples. NMR's utility lies in its capacity to detect and assess biomarkers associated with a plethora of ailments, ranging from cancer and cardiovascular disease to neurological disorders. Additionally, NMR can gauge the concentrations of metabolites in biological samples, furnishing a quantitative evaluation of metabolic alterations linked to disease or condition.

Figure 1. Properties of NMR that allow specific advantages for clinical metabolomics. (Letertre, M.P.M.; et al. 2021)

NMR Services

Creative BioMart Biomarker, a leading purveyor of biomarker services, furnishes a gamut of NMR services, geared towards advancing biomarker discovery and validation. Our comprehensive suite of services includes:

• Biomarker identification: We leverage the power of NMR to discern potential biomarkers in biological samples, endowing us with a panoramic view of metabolic changes linked to disease or condition.
• Biomarker quantification: We employ NMR to ascertain the concentrations of metabolites in biological samples, providing a meticulous and quantitative assessment of metabolic changes associated with disease or condition.
• Biomarker validation: We utilize NMR to verify the accuracy and reliability of prospective biomarkers, underscoring their utility in diagnostic tests or clinical trials.
• Custom NMR services: We offer an extensive range of bespoke NMR services, tailored to the specific needs of our clientele. These include sample preparation, data analysis, and report generation, among others.

Our Advantages

• Expertise: Our team of seasoned scientists is endowed with prodigious knowledge and expertise in NMR and biomarker research, engendering the most superlative results.
• State-of-the-art facilities: We employ cutting-edge NMR facilities and equipment to guarantee the most superior quality data, equipping us with the requisite tools to tackle the most intricate research problems.
• Customization: We offer bespoke NMR services tailored to the specific needs of our clients, culminating in the most personalized and precise results.
• Confidentiality: We uphold stringent confidentiality and data security measures to safeguard our clients' intellectual property and data, imbuing our clients with peace of mind.

At Creative BioMart Biomarker, we provide an array of NMR services for biomarker discovery and validation, ensuring that our clients receive the highest quality data and results. Please feel free to contact us for more information.

Reference:

1. Letertre, M.P.M., et al. Nuclear Magnetic Resonance Spectroscopy in Clinical Metabolomics and Personalized Medicine: Current Challenges and Perspectives. Front Mol Biosci. 2021, 8: 698337.