The study of biomarkers has become a powerful tool for understanding complex diseases and tailoring personalized therapies. Biomarkers are measurable indicators of biological processes that have great potential for disease diagnosis, prognosis and treatment. To harness the power of biomarker analysis, Creative BioMart Biomarker offers cutting-edge tissue microarrays (TMAs) services.
Tissue Microarrays
TMAs allow for the simultaneous analysis of multiple tissue samples on a single microscope slide. By assembling small cores of tissues from a variety of specimens onto a single slide, TMAs enable researchers to efficiently study hundreds or even thousands of samples. The construction of TMAs involves several different steps, including sample collection, embedding, core extraction and array organization. Once a TMA is created, it can be sectioned and analyzed, enabling researchers to examine specific biomarkers in tissue samples. By using TMA, high-throughput biomarker analysis can be performed on a large number of tissue samples to discover new associations between biomarker expression and clinical outcomes.
TMAs Service by Creative BioMart Biomarker
Creative BioMart Biomarker provides customized TMAs services to meet the specific needs of clients. Our expertise, coupled with advanced technologies and a large library of annotated tissue samples, make Creative BioMart Biomarker the ideal partner for tissue biomarker research. Our TMA analysis process follows a clearly defined process to ensure accurate and reliable results:
- Sample Collection and Annotation: Comprehensive tissue library with detailed clinical and pathological annotations. Clients can select samples based on specific criteria, ensuring the relevance and diversity of the tissue cohort.
- Tissue Preparation and TMA Construction: Carefully process selected tissue samples, including embedding in paraffin blocks or freezing to maintain structural integrity. Cylindrical cores are then extracted from the tissue blocks and organized onto recipient blocks or adhesive-coated glass slides.
- Sectioning and Staining: The constructed TMAs are sectioned into thin slices, transferred onto glass slides, and subjected to staining techniques such as immunohistochemistry or in situ hybridization.
- Digital Scanning and Image Analysis: Utilize high-resolution digital scanning of stained slides for efficient data analysis and storage. Image analysis software enables precise quantification and characterization of biomarker expression patterns.
- Data Interpretation and Reporting: Analyze data obtained from TMAs, interpret results in the context of specific research objectives and provide detailed reports.
Why Choose Creative BioMart Biomarker?
- Efficiency and Scalability: Ability to analyze large numbers of tissue samples in a cost-effective and time-efficient manner. Perform high-throughput biomarker studies to accelerate discovery and validation.
- Comprehensive Biomarker Analysis: Analyze a wide range of biomarkers and gain valuable insights into biomarker biology by integrating various analytical techniques, such as immunohistochemistry or in situ hybridization.
- Validation and Translation: Validate biomarkers identified by other high-throughput technologies, such as genomics or proteomics.
Workflow of TMAs Service
TMAs enable the analysis of large numbers of tissue samples in an efficient and cost-effective manner. Creative BioMart Biomarker's TMAs service provides an integrated platform for biomarker analysis, delivering efficient and reliable results. Please feel free to contact us to find out how our TMAs services can assist your tissue biomarker project.
