Single nucleotide polymorphisms (SNPs), the most common type of genetic variation, occur when a single nucleotide within the genome is replaced. In the field of genetic research, SNP genotyping has become a powerful tool for studying human genetic variation and revealing complex relationships between genes and diseases. Identification and analysis of SNPs allows researchers to reveal valuable molecular biomarkers that are key to advances in personalized medicine and targeted therapies. Creative BioMart Biomarker provides customers with personalized SNP genotyping services to facilitate research on biomarkers.
SNP Genotyping and Biomarkers
SNP genotyping is a process that involves the identification and analysis of single nucleotide polymorphisms within an individual's genetic material. SNPs are the most prevalent form of genetic variation that affects an individual's susceptibility to disease, drug response, and overall treatment outcome. By genotyping SNPs, specific genetic markers associated with various phenotypic traits and diseases can be pinpointed.
SNP genotyping plays a key role in biomarker research, contributing to personalized medicine, disease risk assessment, and pharmacogenomics. By identifying specific SNPs associated with disease, researchers can develop diagnostic tests to predict an individual's disease susceptibility and prognosis. Additionally, SNP genotyping facilitates pharmacogenomics research by elucidating how genetic variation affects drug response.
SNP Genotyping Services Offered by Creative BioMart Biomarker
As a pioneer company in the field of biomarker research, Creative BioMart Biomarker provides superior SNP genotyping services for biomarker research. We employ a variety of genotyping methods, including PCR-based techniques, microarray-based methods, and sequencing-based techniques.
- PCR-based genotyping includes allele-specific PCR and TaqMan assays, enabling targeted amplification and detection of SNP alleles. Primers for allele-specific PCR are designed to selectively amplify the target sequence based on the SNP alleles present in the sample. TaqMan assays utilize fluorescent probes to detect the specific SNP allele during amplification.
- Microarray-based genotyping method relies on the hybridization of DNA samples to a microarray containing thousands or millions of SNP-specific probes. The hybridization pattern indicates the presence of specific SNP alleles in a sample, allowing high-throughput analysis of multiple SNPs simultaneously.
- Sequencing-based methods include Sanger sequencing and next-generation sequencing (NGS). Sanger sequencing can directly identify SNP alleles by sequencing the target DNA region and is suitable for analyzing a limited number of SNPs. NGS technologies can simultaneously analyze thousands of SNPs across the genome, providing comprehensive genetic information.
The Flow of SNP Genotyping
Our Advantages
- A variety of advanced genotyping methods are available.
- Ensure accurate and reliable genotyping results.
- Employ powerful statistical and bioinformatics tools to interpret genotyping data.
- Customize solutions to meet specific research goals.
- Comprehensive reports summarizing genotyping results facilitate further analysis and decision making.
With Creative BioMart Biomarker's expertise and state-of-the-art genotyping services, clients can delve into the world of SNPs to discover genetic biomarkers. By harnessing the power of SNP genotyping, we can pave the way for a future where precision diagnosis and customized treatment are the norm. If you are looking for high-quality personalized SNP genotyping services, please feel free to contact us for more detailed information.
