Creative BioMart Biomarker provides accurate, sensitive and specific rheumatoid factors (RFs) testing outsourcing services for scientists in the field of biomarkers or disease researches. Our testing services are only suitable for scientific research, not intended for clinical diagnosis and testing.
|
Rheumatoid Factors Testing |
| Analyte: |
RFs |
| Synonyms: |
rheumatoid factors |
| Sample Type: |
serum, plasma, etc. |
| Assay Platform: |
ELISA |
| Biomarker Application Area: |
bone diseases, such as rheumatoid arthritis (RA) |
| * Perform three replicate tests on each sample, and include appropriate controls in each assay. |
Assay Background
RFs are a class of autoantibodies originally discovered in RA more than half a century ago. RFs are non-specific that are present not only in RA patients, but also in healthy elderly or in patients with other autoimmune and infectious diseases. As the name of the RFs indicates, it is a biomarker commonly used in RA and has always been one of the classification criteria for RA. Its subtypes facilitate the management of RA patients, including diagnosis of RA, provision of prognostic information, prediction of drug response, and identification of subgroups of patients. Secondly, RFs can be used not only to predict the onset of RA but also to predict the development of RA. IgM, IgA and IgG RFs may be detected for many years before the onset of RA. RFs have high detection sensitivity and specificity in RA patients. RFs can bind to self-IgG to form an immune complex (IC), which activates the complement system and destructive inflammation, leading to synovial damage and eventually RA.
Workflow of Biomarker Detection Services at Creative BioMart Biomarker
Customers provide: samples, reagents/kits (reagents/kits can also be provided or purchased by our company).
We provide: remaining samples and reagents, complete experimental reports (including experimental raw data, experimental procedures, instrument and reagent information, and professional result analysis).
Test cycle: 10 working days or less.
Why Choose Creative BioMart Biomarker for RFs Detection Service?
- High-quality ELISA technology platform
Over the years, our expert team has spent a lot of energy to establish a high-quality ELISA technology platform, and select ELISA kits with high sensitivity and specificity for testing to meet the experimental needs of customers.
- Experienced experts team
We have many experts with rich experience in biomarker testing. They always treat each test with a rigorous attitude and can always provide customers with accurate, precise and repeatable test results.
- Suitable for multiple sample types
Our biomarker testing service is applicable to several sample types, including serum, plasma, etc. If your sample type is not common, you can contact us at any time to inquire about the testing service for your sample type.
- Fast testing and reasonable price
We have been committed to providing customers with efficient services to ensure that the experimental results are delivered within the predetermined time. Our testing services have reasonable and competitive prices in the industry, which can help customers reduce research costs.
If you are interested in our services, please feel free to contact us, Creative BioMart Biomarker is here to offer you professional and thoughtful service.
References:
- Ingegnoli, F.; et al. Rheumatoid factors: clinical applications. Disease markers. 2013, 35(6): 727-734.
- Brink, M.; et al. Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis. Arthritis Research & Therapy. 2016, 18(1): 43-53.
