Optical coherence tomography (OCT) is an imaging technique developed for ophthalmic applications that produces high-resolution cross-sectional images. By leveraging Creative BioMart Biomarker's cutting-edge OCT technology and services, our clients can unlock new insights into various diseases and improve patient care by identifying reliable biomarkers.
OCT uses the principle of interferometry to generate detailed, real-time images of tissue microstructure. It uses superluminescent light-emitting diodes or ultrashort pulse lasers to emit low-coherence light to the tissue to be inspected and the rear-view beam, records the time delay of the tissue-reflected light through an interferometer, and uses a rear-view mirror to reflect the light. Then it is converted into a graphic with a resolution of up to 10-20 μm, and it can be reconstructed in three dimensions.
OCT has shown promise in identifying and assessing biomarkers for a range of diseases. Its non-invasiveness, high resolution, and ability to capture real-time images make it an attractive modality for biomarker discovery and monitoring. OCT has been used to identify retinal features associated with neuroinflammatory and neurodegenerative diseases. In lysosomal storage diseases, OCT has been helpful in monitoring retinal degeneration and disease progression.
Figure 1. Example of retinal thickness (RT) as seen on optical coherence tomography (Hanson, R.L.W., et al. 2022)
Creative BioMart Biomarker is at the forefront of providing advanced OCT technology and services for biomarker analysis. With our state-of-the-art OCT systems and expertise, clients receive comprehensive services for:
Our OCT systems provide superior resolution to visualize fine tissue structures and subtle changes associated with various diseases. Customers can obtain detailed cross-sectional and volumetric images, facilitating the identification and quantification of potential biomarkers.
With the ability to capture real-time images, our OCT services can help clients longitudinally monitor disease progression and treatment response. Such longitudinal data can provide valuable insights into the dynamics of biomarkers over time and aid in treatment decisions.
We offer advanced image analysis tools and algorithms tailored to specific biomarker research needs. Our team of experts can assist in the development of custom image analysis workflows, ensuring accurate and reliable quantification of biomarkers and facilitating data interpretation.
OCT has emerged as a powerful tool for biomarker analysis, providing non-invasive imaging with high resolution and real-time capabilities. By utilizing advanced OCT technologies and services provided by Creative BioMart Biomarker, clients can unlock new insights into various diseases, monitor disease progression and identify reliable biomarkers. If you want to know more service related information, please feel free to contact us.
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