Genomic in Situ Hybridization Service

With its unparalleled precision, genomic in situ hybridization (GISH) has become an indispensable asset for researchers seeking to delve deeper into the intricacies of genomic data.

Here at Creative BioMart Biomarker, we pride ourselves on providing nothing but the highest-quality GISH services for biomarkers. Our unwavering commitment to excellence means that our clients can leverage our expertise to accelerate their research and development efforts in the realm of precision medicine. Through the application of GISH, our clients can unlock new insights and achieve breakthroughs that were once considered impossible.

What is Genomic in Situ Hybridization?

GISH is a sophisticated molecular technique that has the power to identify specific DNA sequences within a genome. By labeling a probe DNA sequence with a fluorescent or radioactive molecule and hybridizing it to the chromosomal DNA of interest, researchers can unravel the mysteries of genomic data at the molecular level. With its capacity to analyze entire genomes, GISH can detect chromosomal abnormalities and genetic changes that may be invisible to other techniques. Furthermore, GISH has been used to shed light on the evolution of plant genomes. The interdisciplinary nature of GISH has fostered innovation, propelling the field of biomarker research to new heights.

Figure 1. Genomic in situ hybridization (GISH) mechanism diagram. (Ramzan, F.; et al. 2017)

GISH Services

• Identification of chromosomal abnormalities associated with different types of cancer: The exceptional precision and accuracy of our GISH services can propel your research efforts to new heights.
• Identification of genetic mutations associated with inherited diseases: By enabling earlier diagnosis and more targeted treatment options, our GISH services can help you to stay ahead of the curve in the ever-evolving field of genetic medicine.
• Study of the evolution of plant genomes: By examining the chromosomal changes that occur during plant evolution, we can identify genes responsible for specific traits or functions and further our understanding of the mechanisms by which these genes evolve.
• Identification of genetic variation within a population: With our innovative GISH services, you can gain a deeper understanding of the complex interplay between genetics and disease, fueling new discoveries and breakthroughs.

The Main Steps of GISH

Our Advantages

• Cutting-edge equipment and advanced techniques to ensure the accuracy and reliability of our results.
• GISH services that can be customized to meet the unique needs of our clients.
• Competitive pricing and swift turnaround times enable our customers to accelerate their research and development efforts.

GISH is a powerful tool in biomarker research that facilitates the identification and visualization of DNA sequences in a genome. Creative BioMart Biomarker offers high-quality GISH services for biomarkers that empower our clients to advance their research and development efforts in precision medicine. With our experienced scientists, state-of-the-art equipment, and customized services, we are dedicated to providing precise and dependable results to our clients. Contact us now for more service information.

References:

1. Ramzan, L.; et al. Application of Genomic In Situ Hybridization in Horticultural Science. International Journal of Genomics. 2017, 7561909.
2. Brammer, S. P.; et al. Genomic in situ Hybridization in Triticeae: A Methodological Approach. 2013.