Fluorescence Resonance Energy Transfer (FRET)
In the field of biomedical research, the search for novel biomarkers plays a key role in advancing diagnostic and therapeutic strategies. Fluorescence resonance energy transfer (FRET) is a technique that has emerged as a powerful tool in biomarker research. As a company focusing on the field of biomarkers, Creative BioMart Biomarker provides customers with FRET services for biomarker research.
What is FRET?
FRET is a phenomenon rooted in the principle of fluorescence, in which energy is transferred between two fluorophores in close proximity. A donor fluorophore absorbs a photon and becomes excited, then transfers this energy by a nonradiative mechanism to an acceptor fluorophore with overlapping emission and absorption spectra. The acceptor then emits light at a longer wavelength than the donor, and the efficiency of the energy transfer can be quantified, acting as a molecular ruler for measuring nanoscale distances.
FRET Service Offered by Creative BioMart Biomarker
We offer FRET services tailored for biomarker research. Our laboratory is equipped with advanced fluorescence microscopes and techniques to ensure accurate and quantitative measurement of FRET efficiency. Our team of skilled researchers has extensive experience in designing FRET experiments and analyzing data, providing comprehensive insights into molecular interactions and biomarker dynamics.
- Choose The Right Fluorophore
Selecting the correct donor-acceptor fluorophore pair is fundamental to a successful FRET experiment. Our experts carefully select fluorophores with overlapping emission and absorption spectra, ensuring optimal energy transfer efficiency.
In biomarker research, biomolecules of interest are labeled with donor and acceptor fluorophores. We employ precise and efficient labeling techniques to preserve the function and integrity of biomolecules.
High-quality samples are critical for accurate FRET measurements. Our researchers carefully prepare biological samples, such as cells or tissues, to create the ideal environment for FRET experiments.
We use advanced fluorescence microscopy or techniques to measure the FRET signal in the sample, then process and analyze the acquired data to quantify the FRET efficiency.
Application of FRET in Biomarker Research
- Gain valuable insights into molecular interactions, protein conformational changes, enzyme activity, and receptor-ligand binding. This knowledge is critical for elucidating signaling pathways and identifying potential drug targets.
- Discover and validate novel biomarkers for a variety of diseases, including cancer, infectious disease, and neurodegenerative disease.
- Detect changes in biomarker levels and interactions, enabling earlier disease detection and personalized treatments.
Why Choose Creative BioMart Biomarker for FRET Service?
- Numerous FRET experiments have been successfully performed, generating valuable data for a variety of applications.
- Invest in advanced equipment and technology to ensure the highest quality results.
- Customize FRET services to meet your specific needs.
- Comprehensive reports are provided to accurately interpret FRET results.
Workflow of FRET Service
Creative BioMart Biomarker is dedicated to harnessing the power of FRET to discover and validate novel biomarkers for various diseases. If you are interested in our services, please feel free to contact us.
