| Catalog#: |
MK0190R |
| Product Name: |
Recombinant Rat Csf1r, His tagged |
| Product Overview: |
Recombinant Rat Csf1r (D4ACA7) (Met1-Glu510), fused with a polyhistidine tag at the C-terminus, was produced in HEK293 cells. |
| Description: |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1, a cytokine involved in the proliferation, differentiation, and activation of macrophages. As a member of the typeIII subfamily of receptor tyrosine kinases (RTKs), M-CSF receptor is expressed mainly on cells of monocyte/macrophage lineage, and consists of an extracellular ligand-binding domain and a cytoplasmic protein tyrosine kinase (PTK) domain joined through a single transmembrane helix. Ligand binding induces th |
| Source: |
HEK293 cells |
| Species: |
Rat |
| Tag: |
His |
| Formulation: |
Lyophilized from a sterile solution of PBS, pH 7.4, 5%~8% trehalose and mannitol. |
| Purity: |
>95% as determined by SDS-PAGE. |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| Molecular Mass: |
The recombinant rat CSF1R comprises 502 amino acids and predicts a molecular mass of 56.5 kDa. The apparent molecular mass of the recombinant protein is approximately 69-89 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -70℃. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles. |
