| Catalog#: |
MK0138R |
| Product Name: |
Recombinant Rat Cdh13, His tagged |
| Product Overview: |
Recombinant Rat Cdh13 (NP_620244.1) (Met1-Ala692), fused with a polyhistidine tag at the C-terminus, was produced in HEK293 cells. |
| Description: |
CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer. |
| Source: |
HEK293 cells |
| Species: |
Rat |
| Tag: |
His |
| Formulation: |
Lyophilized from a sterile solution of PBS, pH 7.4, 5%~8% trehalose and mannitol. |
| Purity: |
(69.0+26.9)% as determined by SDS-PAGE |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| Molecular Mass: |
The recombinant rat CDH13 comprises 682 amino acids and predicts a molecular mass of 74.9 kDa. The apparent molecular mass of the recombinant protein is approximately 117 and 95 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -70℃. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles. |
