| Catalog#: |
MK0997M |
| Product Name: |
Recombinant Mouse CD79B Protein, His-tagged |
| Description: |
CD79B (also known as B29, Ig β and B cell antigen receptor complex-associated protein β-chain) is a 36-40 kDa member of the Ig-Superfamily. It is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. |
| Source: |
HEK293 cells |
| Species: |
Mouse |
| Tag: |
His |
| Formulation: |
Lyophilized from 0.22 μm filtered solution in PBS, 200 mM L-arginine (pH 7.4). |
| Protein length: |
Ala29-Asp159 |
| Purity: |
> 95% as determined by BisTris PAGE. |
| Storage: |
Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
15.9 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
Less than 1 EU per μg by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
