| Catalog#: |
MK0992M |
| Product Name: |
Recombinant Mouse CD47 Protein, hFc Chimera |
| Description: |
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers. |
| Source: |
HEK293 cells |
| Species: |
Mouse |
| Tag: |
Fc |
| Formulation: |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Protein length: |
Gln19-Lys140 |
| Purity: |
> 95% as determined by BisTris PAGE. |
| Storage: |
Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
40.60 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
Less than 1 EU per μg by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
