| Product Name: |
Recombinant Mouse BCMA/TNFRSF17, hFc-tagged |
| Catalog#: |
MK0979M |
| Species: |
Mouse |
| Source: |
HEK293 |
| Tag: |
hFc |
| Product Overview: |
Recombinant Mouse BCMA/TNFRSF17 (O88472.1) (Met1-Thr49), fused with a C-terminal hFc tag, was expressed in HEK293 cells. |
| Description: |
BCMA (B-cell maturation antigen), also known as TNFRSF17, is a member of the TNF receptor superfamily that plays a crucial role in B-cell function. It acts as a receptor for the ligands APRIL and BAFF. The binding of these ligands to BCMA provides key signals that stimulate IgM production and promote the survival of B cells. Although expressed on the surface of mature B cells, BCMA is primarily localized to the Golgi compartment. Its essential function in promoting B-cell survival and maturation makes it a critical regulator of humoral immunity and a major therapeutic target in diseases like multiple myeloma. |
| Formulation: |
Formulated in 0.22μm-filtered Phosphate-Buffered Saline (pH 7.4). |
| Purity: |
> 95% as determined by SDS-PAGE. |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Use distilled water to dissolve the protein to a concentration above 100 μg/mL. Aliquot the solution into single-use vials and freeze. |
| Molecular Mass: |
Approximately 31 kDa. |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. Aoid repeated freeze-thaw cycles. |
