| Catalog#: |
MK0984M |
| Product Name: |
Recombinant Mouse AXL Protein, His-tagged |
| Description: |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. |
| Source: |
HEK293 cells |
| Species: |
Mouse |
| Tag: |
His |
| Formulation: |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Protein length: |
His20-Trp445 |
| Purity: |
> 95% as determined by BisTris PAGE. |
| Storage: |
Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
47.8 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
Less than 1 EU per μg by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
