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Recombinant Human TPO, His tagged

Product Information
Catalog#:  MK0759H
Product Name:  Recombinant Human TPO, His tagged
Product Overview:  Recombinant Human TPO (P07202-1) extracellular domain (Met 1- Arg846, 257 Ser/Ala, 725 Pro/Thr), fused with a polyhistidine tag at the C-terminus, was produced in Baculovirus-Insect cells.
Description:  Thyroid peroxidase, also known as TPO, is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It acts as an enzyme and plays a central role in thyroid gland function. Thyroid peroxidase/TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in thyroid peroxidase/TPO gene are associated with several disorders of thyroid ho
Source:  Baculovirus-Insect cells
Species:  Human
Tag:  His
Formulation:  Lyophilized from 0.2μm filtered solution of 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
Storage:  Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Reconstitution:  It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4°C before opening to recover the entire contents.
Molecular Mass:  The secreted recombinant human TPO comprises 842 amino acids and has a predicted molecular mass of 93.8 kDa. ? The apparent molecular mass of rh TPO (1-846) is approximately 90-100 kDa in SDS-PAGE under reducing conditions.
Stability:  Samples are stable for up to twelve months from date of receipt at -70℃.
Endotoxin:  Less than 1.0 EU per μg as determined by the LAL method.
Notes:  Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles.
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