| Product Name: |
Recombinant Human Sigle3/CD33, hFc-tagged |
| Catalog#: |
MK1036H |
| Species: |
Human |
| Source: |
HEK293 |
| Tag: |
hFc |
| Product Overview: |
Recombinant Human Sigle3/CD33 (P20138-1) (Asp18-His259) , fused with a C-terminal hFc tag, was expressed in HEK293 cells. |
| Description: |
Siglec-3, also known as CD33, is a protein specifically expressed on cells of the myelomonocytic lineage. As a member of the Siglec family, its primary function is to recognize and bind to sialic acids, a type of carbohydrate present on other cell surfaces. This interaction is considered crucial for modulating the activity of these myeloid immune cells. |
| Formulation: |
Formulated in 0.22μm-filtered Phosphate-Buffered Saline (pH 7.4). |
| Purity: |
> 95% as determined by SDS-PAGE. |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Use distilled water to dissolve the protein to a concentration above 100 μg/mL. Aliquot the solution into single-use vials and freeze. |
| Molecular Mass: |
Approximately 53.6 kDa |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. Aoid repeated freeze-thaw cycles. |
