| Product Information | |
|---|---|
| Catalog#: | MK0585H |
| Product Name: | Recombinant Human OTUB1, His tagged |
| Product Overview: | Recombinant Human OTUB1 (Q96FW1-1) (Met 1-Lys 271), fused with a polyhistide tag at the N-terminus, was produced in E. coli. |
| Description: | OTUB1 is a cytoplasm protein which belongs to the peptidase C65 family. OTUB1 is a hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. OTUB1 is a regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to antigen rechallenge and no longer respond to their cognate antigen. |
| Source: | E. coli |
| Species: | Human |
| Tag: | His |
| Formulation: | Lyophilized from a sterile solution of PBS, pH 7.4, 20% glycerol. |
| Storage: | Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| Molecular Mass: | The recombinant human OTUB1 consisting of 282 amino acids and has a calculated molecular mass of 32.8 kDa. The apparent molecular mass of the protein is approximately 37 kDa in SDS-PAGE under reducing conditions. |
| Stability: | Samples are stable for up to twelve months from date of receipt at -70℃. |
| Endotoxin: | Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: | Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles. |
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