| Product Name: |
Recombinant Human Nectin-4 Protein, hFc-tagged |
| Catalog#: |
MK1027H |
| Species: |
Human |
| Source: |
HEK293 |
| Tag: |
hFc |
| Product Overview: |
Recombinant Human Nectin-4 protein (Q969V4) (Gly32-Ser349), fused with a C-terminal hFc tag, was expressed in HEK293 cells. |
| Description: |
Nectin-4 is a 66 kDa Type I transmembrane glycoprotein belonging to the Nectin family of the Ig superfamily. It primarily functions in cell adhesion by mediating both homophilic and heterophilic interactions, notably with Nectin-1. Clinically, Nectin-4 is significant as it acts as a receptor for the measles virus, and its mutation is linked to ectodermal dysplasia-syndactyly syndrome, indicating a crucial role in human development. |
| Formulation: |
Formulated in 0.22μm-filtered Phosphate-Buffered Saline (pH 7.4). |
| Purity: |
> 95% as determined by SDS-PAGE. |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Use distilled water to dissolve the protein to a concentration above 100 μg/mL. Aliquot the solution into single-use vials and freeze. |
| Molecular Mass: |
Approximately 61.1 kDa. |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. Aoid repeated freeze-thaw cycles. |
