| Product Name: |
Recombinant Human MMP-9 Protein, His-Avi tagged |
| Catalog#: |
MK1075H |
| Species: |
Human |
| Source: |
HEK293 |
| Tag: |
His-Avi |
| Product Overview: |
Recombinant Human MMP-9 Protein (P14780) (Ala20-Asp707), fused with a C-terminal His-Avi tag, was expressed in HEK293 cells. |
| Description: |
Matrix metalloproteinases (MMPs) are a family of zinc- and calcium-dependent endopeptidases that can degrade all components of the extracellular matrix. MMP-9 (gelatinase B) degrades multiple substrates, including gelatin, type IV and V collagen, elastin, and proteoglycan core proteins. It collaborates with interstitial collagenase (MMP-1) to degrade fibrillar collagen when it degrades its denatured gelatin form. MMP-9 is produced by keratinocytes, monocytes, macrophages, and PMN leukocytes and is present in most inflammatory responses. |
| Formulation: |
Formulated in 0.22μm-filtered Phosphate-Buffered Saline (pH 7.4). |
| Purity: |
> 95% as determined by SDS-PAGE. |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Use distilled water to dissolve the protein to a concentration above 100 μg/mL. Aliquot the solution into single-use vials and freeze. |
| Molecular Mass: |
The protein has a predicted MW of 79.3 kDa. |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. Aoid repeated freeze-thaw cycles. |
