| Catalog#: |
MK0562H |
| Product Name: |
Recombinant Human MKI67, GST tagged |
| Product Overview: |
Recombinant Human MKI67 (P46013-2) mature form (Met1-Pro120), fused with the GST tag at the N-terminus, was produced in E. coli. |
| Description: |
MKI67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. It is also involved in ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition of ribosomal RNA synthesis. MKI67 is known as a cellular marker for proliferation. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. |
| Source: |
E. coli |
| Species: |
Human |
| Tag: |
GST |
| Formulation: |
Lyophilized from a 0.2μm filtered solution of PBS, pH 7.4. |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| Molecular Mass: |
The recombinant human MKI67 /GST chimera consists of 354 amino acids and has a predicted molecular mass of 41 kDa. It migrates as an approximately 37-41 KDa band in SDS-PAGE under reducing conditions. |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -70℃. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles. |
