| Catalog#: |
MK0510H |
| Product Name: |
Recombinant Human KDR, His & GST tagged |
| Product Overview: |
Recombinant Human KDR (NP_002244) (Asp807-Val1356), fused with the N-terminal polyhistidine-tagged GST tag, was produced in Baculovirus-Insect cells. |
| Description: |
Vascular endothelial cell growth factor (VEGF), also known as vascular permeability factor, is an endothelial cell mitogen, which stimulates angiogenesis by binding to specific receptors (VEGFRs) on the surface of vascular endothelial cells. The VEGF ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. All the three receptors for VEGF, VEGFR1~3, belong to CSF-1/PDGF receptor subfamily of receptor tyrosine kinase superfamily (RTKs), and contains s |
| Source: |
Baculovirus-Insect cells |
| Species: |
Human |
| Tag: |
His&GST |
| Formulation: |
Lyophilized from a 0.2μm filtered solution of 50mM Tris, 100mM NaCl, pH 8.0, 10% gly, 2mM GSH |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| Molecular Mass: |
The recombinant human KDR /GST chimera consists of 787 amino acids and has a calculated molecular mass of 89.3 kDa. The recombinant protein migrates as an approximately 110 kDa band in SDS-PAGE under reducing conditions. |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -70℃. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles. |
