| Classification: |
Human Proteins |
| Catalog#: |
MK1331H |
| Product Name: |
Recombinant Human IL-17Ra/CD217 Protein, His-tagged |
| Description: |
Interleukin-17 receptor A (IL-17RA, CD217) is a transmembrane receptor that mediates signaling of IL-17 family cytokines. It is broadly expressed on epithelial, endothelial, and immune cells and plays a critical role in inflammatory and autoimmune responses. IL-17RA is an important target in inflammation, autoimmune disease, and therapeutic antibody research. |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
His |
| Formulation: |
1× PBS, pH 7.4 |
| Proteinlength: |
Leu33-Trp320 |
| Purity: |
Human IL-17Ra / CD217 protein, His tag on SDS-PAGE under reducing (R) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 85.0%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
34.8 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized human IL-17Ra/CD217 protein (His tag) binds to Brodalumab with an EC50 of 0.02610 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
