| Catalog#: |
MK1234H |
| Product Name: |
Recombinant Human Her2 Protein, His&Avi-tagged |
| Description: |
ErbB2, also known as Neu and Her2, is a type I membrane glycoprotein belonging to the ErbB family of tyrosine kinase receptors. It serves as a receptor for the epidermal growth factor (EGF) family of growth factors. Upon activation, ErbB2 triggers the MEMO1-RHOA-DIAPH1 signaling pathway, leading to the phosphorylation and inhibition of GSK3B at the cell membrane. |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
His&Avi |
| Formulation: |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Protein length: |
Thr23-Thr652 |
| Purity: |
> 95% as determined by Bis-Tris PAGE.
> 95% as determined by HPLC. |
| Storage: |
Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
72.3 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
Less than 1 EU per μg by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
