| Product Information | |
|---|---|
| Classification: | Human Proteins |
| Catalog#: | MK1310H |
| Product Name: | Recombinant Human ERBB2/HER2/CD340 Protein, His-tagged |
| Description: | HER2 (ERBB2) is a receptor tyrosine kinase involved in cell growth and differentiation. It is overexpressed in certain cancers, particularly breast cancer, and is a target for targeted therapies like trastuzumab. |
| Source: | HEK293 cells |
| Species: | Human |
| Tag: | His |
| Formulation: | 1× PBS, pH 7.4 |
| Proteinlength: | Thr23-Thr652 |
| Purity: | Human ERBB2 / HER2 / CD340 protein, His tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. The purity of the protein is greater than 95.0%. |
| Storage: | For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: | 70.85 kDa |
| Stability: | Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: | <0.001 EU/μg |
| Concentration: | 1 mg/mL |
| Quality Control: | Immobilized human ERBB2/HER2/CD340 protein (His tag) binds to anti-ERBB2/HER2/CD340 antibody with an EC50 of 0.02394 μg/mL. |
| Notes: | Research Use Only. Not for use in clinical procedures. |
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