| Product Name: |
Recombinant Human EGFRVIII Protein, His-Avi tagged, PE-Labeled |
| Catalog#: |
MK1029H |
| Species: |
Human |
| Source: |
HEK293 |
| Tag: |
His-Avi |
| Product Overview: |
Recombinant PE-Labeled Human EGFRVIII Protein (NP_001333870.1) (Leu25-Ser378) fused with a C-terminal His-Avi tag, was expressed in HEK293 cells. |
| Description: |
EGFRvIII is a tumor-specific variant of the Epidermal Growth Factor Receptor (EGFR) that is exclusively expressed in cancer cells and absent from normal tissues. This mutation is highly tumorigenic and confers an aggressive phenotype characterized by enhanced proliferation, invasion, angiogenesis, and evasion of apoptosis. |
| Formulation: |
Formulated in 0.22μm-filtered Phosphate-Buffered Saline (pH 7.4). |
| Purity: |
> 95% as determined by SDS-PAGE. |
| Storage: |
Store the samples at -85 to -65℃. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Use distilled water to dissolve the protein to a concentration above 100 μg/mL. Aliquot the solution into single-use vials and freeze. |
| Molecular Mass: |
The protein has a predicted MW of 41.6 kDa same as SDS-PAGE result. |
| Stability: |
Store the samples at -85 to -65℃. The validity period is 6 months after receipt. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Recommended to aliquot evenly into single-use portions. After alitioning, store at -80℃. |
