| Classification: |
Human Proteins |
| Catalog#: |
MK1309H |
| Product Name: |
Recombinant Human DLL3 Protein, Fc-tagged |
| Description: |
Delta-like protein 3 (DLL3) is a ligand of the Notch signaling pathway that is overexpressed in neuroendocrine tumors, particularly small cell lung cancer. It is a potential target for cancer immunotherapy. |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
Fc |
| Formulation: |
1× PBS, pH 6 |
| Proteinlength: |
Ala27-Leu492 |
| Purity: |
Human DLL3 protein, Fc tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 85.0%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
149.2 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized human DLL3 protein (Fc tag) binds to rovalpituzumab with an EC50 of 0.053150 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
