| Classification: |
Human Proteins |
| Catalog#: |
MK1304H |
| Product Name: |
Recombinant Human CEA Protein, Fc-tagged |
| Description: |
Carcinoembryonic antigen (CEA) is a glycoprotein expressed in fetal tissues and overexpressed in various cancers, particularly colorectal cancer. It is used as a tumor marker in clinical diagnostics and cancer immunotherapy. |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
Fc |
| Formulation: |
0.1 M Na3C6H5O7·2H2O, 0.2 M NaCl, pH 5 |
| Proteinlength: |
Lys35-Ala685 |
| Purity: |
Human CEA protein, Fc tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 85.0%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
194.8 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized human CEA protein (Fc tag) binds to anti-CEACAM5/CEA/CD66e reference antibody (cergutuzumAb) with an EC50 of 0.06043 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
