| Catalog#: |
MK1209H |
| Product Name: |
Recombinant Human CD73 Protein, His-tagged |
| Description: |
CD73, also known as ecto-5'-nucleotidase, is an enzyme that in humans is encoded by the NT5E gene. CD73 commonly serves to convert AMP to adenosine. The enzyme consists of a dimer of 2 identical 70 kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. A deficiency of CD73 occurs in a variety of immunodeficiency diseases. |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
His |
| Formulation: |
Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 120 mM NaCl (pH 7.5). |
| Protein length: |
Trp27-Lys547 |
| Purity: |
> 95% as determined by Bis-Tris PAGE. |
| Storage: |
Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O up to 100 μg/mL. |
| Molecular Mass: |
58.8 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
≤ 1 EU/μg of protein by LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
