| Catalog#: |
MK1187H |
| Product Name: |
Recombinant Human CD38 Protein |
| Description: |
CD38 (also referred to as T10 antigen) is a nonlineage-restricted type II transmembrane glycoprotein that has emerged as an intracellular calcium ion mobilizing messenger. It can serve as an ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose. The enzymatic functions of CD38 probably contribute to an array of its immunoregulatory functions. It has been found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. Soluble CD38 and the ability of membrane-bound CD38 to become internalized in response to appropriate stimuli suggest that extracellular and intracellular roles for this protein are equally plausible. |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
None |
| Protein length: |
Val43-Ile300 |
| Purity: |
> 95% as determined by SDS-PAGE. |
| Storage: |
Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/mL. |
| Molecular Mass: |
~35.7 kDa, on SDS-PAGE under reducing conditions. |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
< 1 EU/μg of protein by gel clotting method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
