| Catalog#: |
MK1172H |
| Product Name: |
Recombinant Human CD24 Protein, Fc Chimera |
| Description: |
Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a protein that in humans is encoded by the CD24 gene. CD24 is a cell adhesion molecule. CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The encoded protein is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. The protein also contributes to a wide range of downstream signaling networks and is crucial for neural development. Cross-linking of CD24 on the surface of neutrophils induces apoptosis, and this appears to be defective in sepsis. |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
Fc |
| Protein length: |
Ser27-Gly59 |
| Purity: |
> 90% as determined by SDS-PAGE. |
| Storage: |
Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/mL. |
| Molecular Mass: |
~42 kDa, on SDS-PAGE under reducing conditions. |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
< 1 EU/μg of protein by gel clotting method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
