| Catalog#: |
MK0054H |
| Product Name: |
Recombinant Human C7, Fc tagged |
| Product Overview: |
Recombinant Human C7 (P10643) (Met1-Gln843), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cell. |
| Description: |
Complement component 7 is a member of the complement C6/C7/C8/C9 family. It contains 1 EGF-like domain, 1 LDL-receptor class A domain, 1 MACPF domain, 2 Sushi (CCP/SCR) domains and 2 TSP type-1 domains. As a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. As a constituent of MAC, it plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cel |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
Fc |
| Formulation: |
Lyophilized from a 0.2μm filtered solution of PBS, pH 7.4. |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| Molecular Mass: |
The recombinant human C7 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 1062 amino acids and has a predicted molecular mass of 118 kDa. The apparent molecular mass of the protein is approximately 118 kDa in SDS-PAGE under reducing conditions. |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -70℃. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles. |
