| Classification: |
Human Proteins |
| Catalog#: |
MK1288H |
| Product Name: |
Recombinant Human B7-H1/PD-L1/CD274 Protein, Fc-tagged |
| Description: |
PD-L1 (B7-H1) is a key immune checkpoint protein that inhibits T-cell activation, playing a central role in immune evasion by tumors. It is a major target in cancer immunotherapy. |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
Fc |
| Formulation: |
0.1 M Na3C6H5O7·2H2O, 0.2 M NaCl, pH 5 |
| Proteinlength: |
Met1-Thr239 |
| Purity: |
Human B7-H1 / PD-L1 / CD274 protein, Fc tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. The purity of the protein is 97.0%. |
| Storage: |
For long term storage, the product should be stored at lyophilized state at -20 °C or lower. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
103 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
＜0.001 EU/μg |
| Concentration: |
1 mg/mL |
| Quality Control: |
Immobilized human B7-H1/PD-L1/CD274 protein (Fc tag) binds to anti-B7-H1/PD-L1/CD274 antibody with an EC50 of 0.02369 μg/mL. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
