| Product Information | |
|---|---|
| Product Name: | Recombinant Human AXL Protein, hFc tagged, Ultra Low Endotoxin |
| Catalog#: | MK1129H |
| Species: | Human |
| Source: | HEK293 |
| Tag: | hFc |
| Product Overview: | Recombinant Human AXL Protein (P30530-1) (Ala26-Pro449), fused with a C-terminal hFc tag,Ultra Low Endotoxin, was expressed in HEK293 cells. |
| Description: | Axl, part of the TAM family, and its inhibitors can disrupt kinase signaling, helping patients regain drug sensitivity and improve treatment outcomes. Axl overexpression and activation are known to drive cell proliferation, chemotherapy resistance, and metastasis in cancers like lung, breast, and pancreatic. |
| Formulation: | Formulated in 0.22μm-filtered Phosphate-Buffered Saline (pH 7.4). |
| Purity: | > 95% as determined by SDS-PAGE. |
| Storage: | Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: | Use distilled water to dissolve the protein to a concentration above 100 μg/mL. Aliquot the solution into single-use vials and freeze. |
| Molecular Mass: | The protein has a predicted MW of 72.6 kDa. |
| Stability: | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. |
| Endotoxin: | Less than 0.01 EU per μg by the LAL method. |
| Notes: | Research Use Only. Not for use in clinical procedures. Aoid repeated freeze-thaw cycles. |
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