Recombinant Human Anti-Mullerian Hormone

Product Information
Catalog#:	MK0954H
Product Name:	Recombinant Human Anti-Mullerian Hormone
Product Overview:	RecombinantHuman AMH protein was expressed in E. coli.
Description:	AMH is atissue-specific TGF-β superfamily growth factor. Its expression is restrictedto the Sertoli cells of fetal and postnatal testis, and to the granulosacells of postnatal ovary. The human MIS gene encodes a 553 amino acid residue(aa) prepropeptide containing a signal a sequence (1-24), a proregion (25-455),and the carboxylterminal bioactive protein (44-6553). MIS is synthesized andsecreted as a disulfide-linked homodimeric pro-protein. Proteolytic cleavageis required to generate the N-terminal pro-region and the C-terminal bioactiveprotein, which remain associated in a noncovalent complex.
Source:	E. coli
Species:	Human
Tag:	N/A
Formulation:	Lyophilizedfrom a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
Bio-activity:	Measuredby its ability to inhibit growth of OVCAR-3 human ovarian carcinoma cells. Measuredby its binding ability in a functional ELISA. Immobilized rhMIS at 3 μg/Ml (100μL/well) will bind rrMIS RII/Fc Chimera with a linear range of 1.6-100 ng/mL.
Protein length:	Ala453-Arg560
Purity:	>97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage:	Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Reconstitution:	Reconstituteat 10μg/mL in sterile PBS containing at least 0.1% human or bovine serumalbumin.
Molecular Mass:	11.7 kDa (monomer)
Endotoxin:	<1.0EU per 1μg of the protein by the LAL method.

Product Information

Catalog#:

MK0954H

Product Name:

Recombinant Human Anti-Mullerian Hormone

Product Overview:

RecombinantHuman AMH protein was expressed in E. coli.

Description:

AMH is atissue-specific TGF-β superfamily growth factor. Its expression is restrictedto the Sertoli cells of fetal and postnatal testis, and to the granulosacells of postnatal ovary. The human MIS gene encodes a 553 amino acid residue(aa) prepropeptide containing a signal a sequence (1-24), a proregion (25-455),and the carboxylterminal bioactive protein (44-6553). MIS is synthesized andsecreted as a disulfide-linked homodimeric pro-protein. Proteolytic cleavageis required to generate the N-terminal pro-region and the C-terminal bioactiveprotein, which remain associated in a noncovalent complex.

Source:

E. coli

Species:

Human

Tag:

N/A

Formulation:

Lyophilizedfrom a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.

Bio-activity:

Measuredby its ability to inhibit growth of OVCAR-3 human ovarian carcinoma cells. Measuredby its binding ability in a functional ELISA. Immobilized rhMIS at 3 μg/Ml (100μL/well) will bind rrMIS RII/Fc Chimera with a linear range of 1.6-100 ng/mL.

Protein length:

Ala453-Arg560

Purity:

>97%,by SDS-PAGE under reducing conditions and visualized by silver stain.

Storage:

Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.

Reconstitution:

Reconstituteat 10μg/mL in sterile PBS containing at least 0.1% human or bovine serumalbumin.

Molecular Mass:

11.7 kDa (monomer)

Endotoxin:

<1.0EU per 1μg of the protein by the LAL method.

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Recombinant Human Anti-Mullerian Hormone