| Catalog#: |
MK0005H |
| Product Name: |
Recombinant Human ADM, Fc tagged |
| Product Overview: |
Recombinant Human ADM (P35318) (Tyr95-Tyr146), fused with the Fc region of human IgG1 at the N-terminus, was produced in Human Cell. |
| Description: |
Adrenomedullin is a a hypotensive peptide which consists of 52 amino acids and belongs to the adrenomedullin family. It has 1 intramolecular disulfide bond, and seems to has a slight homology with the calcitonin gene-related peptide. Adrenomedullin is highly expressed in pheochromocytoma and adrenal medulla. It also can be detected in lung, ventricle and kidney tissues. Adrenomedullin and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologi |
| Source: |
HEK293 cells |
| Species: |
Human |
| Tag: |
Fc |
| Formulation: |
Lyophilized from a 0.2μm filtered solution of PBS, pH 7.4. |
| Protein length: |
Tyr95-Tyr146 |
| Storage: |
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| Molecular Mass: |
The recombinant human ADM/Fc is a disulfide-linked homodimer. The reduced monomer comprises 340 amino acids and has a predicted molecular mass of 38 kDa. The apparent molecular mass of the protein is approximately 39 in SDS-PAGE under reducing conditions due to glycosylation. |
| Stability: |
Samples are stable for up to twelve months from date of receipt at -70℃. |
| Endotoxin: |
Less than 1.0 EU per μg as determined by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures.Aoid repeated freeze-thaw cycles. |
