| Product Information | |
|---|---|
| Catalog#: | MK0823C |
| Product Name: | Recombinant Cynomolgus Nectin-4 Protein, His-tagged |
| Description: | Nectin-4 is a tumor-associated antigen. It is probably involved in cell adhesion through trans-homophilic and -heterophilic interactions. Nectin-4 is overexpressed in urothelial carcinoma and several other malignancies. It is a promising target for antibody-drug conjugates (ADCs). |
| Source: | HEK293 cells |
| Species: | Cynomolgus |
| Tag: | His |
| Formulation: | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Protein length: | Gly32-Val351 |
| Purity: | > 95% as determined by Bis-Tris PAGE. |
| Storage: | Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: | 35.9 kDa |
| Stability: | Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: | Less than 1 EU per μg by the LAL method. |
| Notes: | Research Use Only. Not for use in clinical procedures. |
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