| Product Information | |
|---|---|
| Catalog#: | MK0817C |
| Product Name: | Recombinant Cynomolgus LRRC15/LIB Protein, His&Avi-tagged, Biotinylated |
| Description: | The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. |
| Source: | HEK293 cells |
| Species: | Cynomolgus |
| Tag: | His&Avi |
| Formulation: | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Protein length: | Tyr22-Gly538 |
| Purity: | > 95% as determined by BisTris PAGE. |
| Storage: | Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: | 61.50 kDa |
| Stability: | Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: | Less than 1 EU per μg by the LAL method. |
| Notes: | Research Use Only. Not for use in clinical procedures. |
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