| Catalog#: |
MK0818C |
| Product Name: |
Recombinant Cynomolgus LRRC15/LIB Protein, His-tagged |
| Description: |
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. |
| Source: |
HEK293 cells |
| Species: |
Cynomolgus |
| Tag: |
His |
| Formulation: |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Protein length: |
Tyr22-Gly538 |
| Purity: |
> 95% as determined by Bis-Tris PAGE. |
| Storage: |
Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
| Molecular Mass: |
58.92 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
Less than 1 EU per μg by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
