| Catalog#: |
MK0813C |
| Product Name: |
Recombinant Cynomolgus DLL3 Protein, His-tagged |
| Description: |
Delta-like ligand 3 (DLL3) is an inhibitory Notch ligand. It is highly expressed on the surface of Small cell lung cancer (SCLC) and other neuroendocrine tumors. And its expression promotes SCLC migration and invasion. DLL3 agents are evaluated in several ongoing clinical studies in SCLC and other neuroendocrine tumors. |
| Source: |
HEK293 cells |
| Species: |
Cynomolgus |
| Tag: |
His |
| Formulation: |
Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 200 mM NaCl, 200 mM L-arginine (pH 8.5). |
| Protein length: |
Ala27-Arg488 |
| Purity: |
> 95% as determined by Bis-Tris PAGE. |
| Storage: |
Store under sterile conditions at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles. |
| Reconstitution: |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O up to 100 μg/mL. |
| Molecular Mass: |
49.21 kDa |
| Stability: |
Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. |
| Endotoxin: |
Less than 1 EU per μg by the LAL method. |
| Notes: |
Research Use Only. Not for use in clinical procedures. |
